The Barts Health adult allergy service is one of the country’s leading specialist centres, providing the very latest facilities and treatments for patients at St Bartholomew’s Hospital.
We provide specialist care for a range of conditions in adults (age 16+):
- Allergy to wasp or bee venom
- Anaphylaxis
- Chronic urticaria
- Drug allergy
- Food allergy
- Moderate to Severe rhinitis
- Latex allergy
Why choose us?
We are commissioned by NHS England and we provide specialised treatments such as immunotherapy (desensitisation) and biologic injections, as well as day case challenge testing with foods and drugs.
We accept referrals from GPs and other consultants and provide a holistic and multidisciplinary approach with doctors, nurse specialists, dietitians and specialised pharmacists.
We offer a one-stop clinic in which you will be assessed by one of our specialists. You will receive an appropriate allergy test and be given a self-management plan, with input from our specialist dietitian and nurse specialist.
Our aim is to see and diagnose most patients in just one visit, with further follow-up readily available if necessary. We use a number of different techniques and clinics to test for allergies which are listed below.
Tests and treatments
Skin prick test
A small needle (lancet) is used to gently prick the skin through a droplet of fluid containing a known allergen. If the skin around the needle prick becomes itchy, red and swollen, in combination with a suggestive history, we are likely to be able to confirm your allergy. You will need to stop taking antihistamines for at least 72 hours before the test.
Challenge test
Challenge tests are used in cases where it is not possible to test for an allergy using a simple skin prick test or blood test in clinic e.g. in drug allergy or in cases of food allergy where the initial tests are inconclusive. Challenge testing is undertaken as a day case admission. It involves administering the substance that you are suspected to be allergic to. In the cases of drugs, this will be either by mouth or by injection depending on the drug. Therefore this kind of testing is under close medical supervision.
For some drugs, skin tests are also carried out at the same session. If skin tests are positive, the challenge test may not be required. Full information about these tests, including written information, is given to you before we go ahead.
Intradermal skin test
A very small amount of the drug is injected just below the skin using a small needle in your forearm to create a small bleb (swelling). A positive reaction will cause an increase in the size of the bleb with redness and itching.
Specific IgE blood test
This is another way to test for allergies by taking a sample of blood and measuring the allergic antibodies (chemicals) in the bloodstream. It is suitable for patients unable to have skin prick tests, for example, those who cannot stop taking antihistamines or who have severe skin conditions, or where further information is needed after skin prick testing.
Prick test using fresh foods
You will need to bring in foods that you suspect you are allergic to which we will use for testing. A lancet is used to prick the food and then, the same lancet is used to prick your skin. After 15 minutes, the site is inspected to check for any reaction such as swelling.
Adrenaline auto-injector pen training
Anaphylaxis is a severe allergic reaction with airway obstruction (difficulty in swallowing or breathing) or a drop in blood pressure (feeling faint or collapsing). The immediate treatment for this is adrenaline. After an extreme allergic reaction, you should always be seen in an emergency department and referred on to an allergy clinic.
If you are at risk of anaphylaxis, you will be prescribed an adrenaline auto-injector pen. There are three widely-used types of auto-injector pen: the Epipen, Emerade and Jext. They contain a single dose of adrenaline that can be injected into the body. The adrenaline helps open to the airways so that you can breathe and reverse any fall in blood pressure. Our nurse specialist will give you advice and practical training, using a ‘dummy’ pen for demonstrations.
Allergen immunotherapy
This treatment may be helpful for patients with severe allergic rhinitis due to pollens, animal dander or dust mite, when they have not responded to conventional treatment. It is also beneficial in those with significant with bee or wasp venom allergy. The aim is to help the body tolerate the allergen so that in the long-term any reaction is not so severe and medication can be reduced.
A consultant will assess your suitability, and then if appropriate, you will start a three-year course of treatment. This involves having either subcutaneous injections (under the skin; used for both airborne and venom allergens) or sublingual tablets (dissolved under the tongue; used for airborne allergens but not venoms). You will be closely monitored after each injection, in case there are any side effects.
Biologics
This treatment is suitable for patients with severe chronic spontaneous urticaria who have not responded to conventional treatment. It involves up to six injections of anti-IgE monoclonal antibodies, at four weekly intervals. Suitable candidates are offered the chance to self-inject at home, after training, once they are established on the injections.
For clinicians
We accept referrals from GPs and other hospitals for allergy conditions as above. Treatments include allergen immunotherapy, biologic therapy and challenge testing.
We will not accept a referral for patients with:
- Urticaria/angioedema of less than three months duration. In these patients, symptoms may resolve spontaneously
- Gastrointestinal symptoms who have not identified a specific allergen - referral to a Gastroenterology clinic may be a preferable first step.
We do not offer patch testing. This is offered by dermatology at The Royal London Hospital.
For patients aged under 16, please refer to the paediatric allergy service at The Royal London Hospital.
Allergy Service referral information for clinicians [pdf] 146KB