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Photo of Dr Konstantinos Savvatis

Dr Konstantinos Savvatis

Consultant at St Bartholomew's Hospital

Konstantinos Savvatis is a Consultant Cardiologist in the Inherited Cardiovascular Diseases Unit at the Barts Heart Centre in London and Honorary Associate Professor at University College London and Queen Mary University London.

He trained at the Department of Cardiology at the Charité University Hospital in Berlin, Germany, one of the largest centres in Europe focusing on dilated and inflammatory cardiomyopathy.

He acquired his PhD on the immunomodulatory role of matrix metalloproteinases in acute myocarditis and continued working as a clinician scientist at the Charité and the Centre for Regenerative Therapies, focusing on the role of fibrosis and fibroblasts in heart failure and cardiomyopathy.

Konstantinos' main clinical and academic interests are genetic and inflammatory cardiomyopathies and, especially, the risk assessment and therapy of patients with dilated cardiomyopathy, hypertrophic and arrhythmogenic cardiomyopathy, myocarditis and cardiac involvement in neuromuscular conditions (limb girdle, Duchenne and Becker’s muscular dystrophy, myotonic dystrophy, Friedreich’s ataxia).

He is specialised in advanced cardiovascular MRI and echocardiography.

His work has been published in several high impact journals, such as Nature Communications, Circulation, Circulation Research and European Heart Journal.

Treatments and procedures

Treatments:
•    Hypertrophic cardiomyopathy
•    Dilated cardiomyopathy
•    Arrhythmogenic cardiomyopathy
•    Restrictive cardiomyopathy
•    Inflammatory cardiomyopathy
•    Myocarditis
•    Cardiac involvement in neuromuscular conditions (myotonic dystrophy, Duchenne/Becker’s muscular dystrophy, limb-girdle muscular dystrophy, mitochondrial diseases)
•    Heart failure
•    Athletic heart

Procedures:
•    Electrocardiography
•    Echocardiogram
•    Bubble-echocardiogram
•    Stress echocardiogram (dobutamine and exercise)
•    Cardiopulmonary exercise test (incl. combined with stress echocardiogram)
•    Transoesophageal echocardiogram
•    Cardiac magnetic resonance imaging (MRI)
•    Holter monitor
•    Exercise treadmill test

Research interests

  • Myocarditis and inflammatory cardiomyopathy
  • Myocardial scar tissue formation
  • Risk of sudden death in hypertrophic and dilated cardiomyopathy
  • Neuromuscular conditions with cardiac involvement (LMNA, mitochondrial)
  • Myocardial mechanics in athletic heart, dilated cardiomyopathy, cardio-oncology)
  1. Creta, A., Providencia, R., Gossios, T., Elliott, P. M., Turner, C., Savvatis, K., & Segal, O. R. (2021). A Normal Electrocardiogram Does Not Exclude Infra-Hisian Conduction Disease in Patients With Myotonic Dystrophy Type 1. JACC Clin Electrophysiol. doi
  2. Gossios, T. D., Savvatis, K., Zegkos, T., Parcharidou, D., Karvounis, H. I., & Efthimiadis, G. K. (2021). Risk prediction models and scores in hypertrophic cardiomyopathy. Curr Pharm Des. doi:10.2174/1381612827666210125121115
  3. Protonotarios, A., & Savvatis, K. (2021). Myocardial strain analysis in family screening for genetic dilated cardiomyopathy: Testing the boundaries of normality? Int J Cardiol, 323, 201-202. doi:10.1016/j.ijcard.2020.10.059
  4. Guzik, T. J., Mohiddin, S. A., Dimarco, A., Patel, V., Savvatis, K., Marelli-Berg, F. M., . . . McInnes, I. B. (2020). COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Cardiovasc Res, 116(10), 166

Leadership roles

•    Honorary Associated Professor Institute for Cardiovascular Sciences, University College London
•    Honorary Senior Clinical Lecturer, William Harvey Research Institute, Queen Mary  University London
 
Speciality
Consultant services Cardiology,Cardiovascular
Languages Spoken English
GMC number 7362578
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